This book offers pathologists, toxicologists, other medical professionals, and students an introduction to the discipline and techniques of neuropathology – including chemical and environmental, biological, medical, and regulatory details important for performing an analysis of toxicant-induced neurodiseases. In addition to a section on fundamentals, the book provides detailed coverage of current practices (bioassays, molecular analysis, and nervous system pathology) and practical aspects (data interpretation, regulatory considerations, and tips for preparing reports).

BRAD BOLON, DVM, MS, PhD, Diplomate ACVP, Diplomate ABT, Fellow ATS, Fellow IATP, has spent over twenty years as a practitioner and teacher of toxicologic neuropathology. He is the founder of GEMpath, Inc., an experimental pathology consultancy specializing in drug discovery research.

MARK T. BUTT, DVM, Diplomate ACVP, is the founder of Tox Path Specialists, LLC, a company that provides neuropathology and histology support to pharmaceutical and biotechnology firms developing novel therapies that target nervous system diseases. He has over twenty years' experience providing neuropathology support and has evaluated over four hundred studies supporting regulatory submissions for neuroactive compounds.