{"product_id":"9780470191156","title":"Assay Development Fundamentals and Practices","description":"\u003ch1\u003eAssay Development\u003c\/h1\u003e\u003ch2\u003eFundamentals and Practices\u003c\/h2\u003e\u003ch3\u003eGe Wu\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Biotechnology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003eEssential principles and practice of assay development\u003c\/p\u003e \u003cp\u003eThe first comprehensive, integrated treatment of the subject, Assay Development: Fundamentals and Practices covers the essentials and techniques involved in carrying out an assay project in either a biotechnology\/drug discovery setting or a platform setting.\u003c\/p\u003e \u003cp\u003eRather than attempting comprehensive coverage of all assay development technologies, the book introduces the most widely used assay development technologies and illustrates the art of assay development through a few commonly encountered biological targets in assay development (e.g., proteases, kinases, ion channels, and G protein-coupled receptors). Just enough biological background for these biological targets is provided so that the reader can follow the logics of assay development. Chapters discuss:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eThe basics of assay development, including foundational concepts and applications\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eCommonly used instrumental methods for both biochemical assays and cell-based assays\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eAssay strategies for protein binding and enzymatic activity\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eCell-based assays\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eHigh-throughput screening\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eAn in-depth study of the now popular Caliper's off-chip kinase assay provides an instructive, real-world example of the assay development process.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003eGe Wu, PhD, is Director of Assay Development at Iris International. He obtained his doctorate in biochemistry from UCLA, performed postdoctoral work at Harvard Medical School, and was a member of the faculty at Cornell University Medical College. Prior to joining Iris International, he worked at Merck \u0026amp; Co., Caliper Technologies, Amphora Discovery, and FivePrime Therapeutics. He is the founding Director of Assay Development and Screening at FivePrime Therapeutics. Dr. Wu is a leading figure in assay development and screening in biopharmaceutical discovery using primary cell assay and the author of an acclaimed review in this subject.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e26 April 2010\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470191156\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e452\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e26.88\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44384205275276,"sku":"9780470191156","price":175.46,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470191156.jpg?v=1780174738","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470191156","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}