{"product_id":"9780470175576","title":"Vanilloid Receptor TRPV1 in Drug Discovery Targeting Pain and Other Pathological Disorders","description":"\u003ch1\u003eVanilloid Receptor TRPV1 in Drug Discovery\u003c\/h1\u003e\u003ch2\u003eTargeting Pain and Other Pathological Disorders\u003c\/h2\u003e\u003ch3\u003eArthur Gomtsyan | Connie R. Faltynek\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cb\u003eExamines the emerging therapeutic role of TRPV1\u003c\/b\u003e  \u003cp\u003eTRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain transmission pathways. Because of its potential for managing multiple pain types, including osteoarthritis, chronic low back pain, neuropathic pain, and cancer pain, some consider it \"the holy grail\" of pain management. This dedicated reference summarizes available data related to the potential therapeutic utility for TRPV1 ligands.\u003c\/p\u003e \u003cp\u003eWith contributions from many of the world's leading experts on TRP channels, \u003ci\u003eVanilloid Receptor TRPV1 in Drug Discovery\u003c\/i\u003e covers the important TRPV1 target for drugs to treat painful conditions such as inflammation, arthritis, and cancer pain. The book discusses:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eRecent advances in biology, chemistry, and pharmacology at both the preclinical and clinical stage of the dynamic area of TRPV1 drug discovery research\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eThe potential for drugs targeting TRPV1 in painful conditions such as inflammation, arthritis, and cancer\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eThe development of analgesic drugs\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eOther applications for TRPV1, including the treatment of respiratory disease and diabetes\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eFeaturing data relevant to the therapeutic potential of TRPV1 and the medicinal chemistry involved in designing TRPV1 antagonists, \u003ci\u003eVanilloid Receptor TRPV1 in Drug Discovery\u003c\/i\u003e is a key tool for researchers in the pharmaceutical industry and academia involved in pain, ion channels, and analgesic drug development.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cb\u003eARTHUR GOMTSYAN\u003c\/b\u003e is an Associate Research Fellow at Abbott Laboratories where he focuses on neuroscience research and pain drug targets. He is on the editorial board of two peer-reviewed journals and has over forty scientific articles to his credit.  \u003cp\u003e\u003cb\u003eCONNIE R. FALTYNEK\u003c\/b\u003e is a Director for Neuroscience and Pain Discovery at Abbott Laboratories. She has twenty years' experience in drug discovery research in the pharmaceutical industry and has published nearly 100 scientific papers.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e01 March 2010\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470175576\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e488\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e27.84\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44310531342476,"sku":"9780470175576","price":166.46,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470175576_b9d0ba4d-37b9-441a-9d95-bb04f1442cb5.jpg?v=1780163040","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470175576","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}