Integrated Drug Design and Discovery: Medicinal Chemistry, Combinatorial Synthesis, and Computational Technology

Chen, Zhengming

In recent years, the process of drug discovery has undergone a gradual paradigm shift from “industrializing” to “intellectualizing.” This trend involves integrating medicinal chemistry, combinatorial synthesis, and computational technology. Illuminating this new approach, Integrated Drug Design and Discovery gives information on the practical issues and applications of computational techniques in drug design and discovery. It provides an overview of current methods to improve early-stage drug screening efficiency, and discusses key conceptual issues faced in drug lead generation. Case studies and examples emphasize drug design, lead generation, and lead optimization.

Details

Published by: Wiley-Interscience

Publication Date: 2011-05-16

Format: Hardcover

ISBN-13: 9780470168431

DOI:

Dimensions: cm xcm

Pages: 676