{"product_id":"9780470093733","title":"Nuclear Organization in Development and Disease","description":"\u003ch3\u003eNovartis Foundation Symposia\u003c\/h3\u003e\u003ch1\u003eNuclear Organization in Development and Disease\u003c\/h1\u003e\u003ch3\u003eDerek J. Chadwick | Jamie A. Goode\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Life Sciences \/ Biochemistry\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eThis book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular basis of these diseases. Topics include:  \u003cul\u003e \u003cli\u003eHow nuclear structure and location within a nucleus affect gene expression\u003c\/li\u003e \u003cli\u003eChromatin organization and cell differentiation\u003c\/li\u003e \u003cli\u003eThe nature of the interactions between the nuclear envelope and the cytoskeleton\u003c\/li\u003e \u003cli\u003eThe extent to which the cytoskeleton mediates communication between the cell membrane and nucleus in regulating gene expression and whether disruption of such communication might underlie the disease processes\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eIt is hoped that a better understanding of the mechanisms leading to disease pathogenesis may ultimately lead to more rational and appropriate treatments.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cb\u003eThe Novartis Foundation\u003c\/b\u003e is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.\u003cbr\u003e Chair: \u003cb\u003eRobert D. Goldman\u003c\/b\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e04 March 2005\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470093733\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e300\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e21.28\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44384928497804,"sku":"9780470093733","price":190.76,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470093733_e145715d-6062-4741-a7ae-73c8db552f08.jpg?v=1780203548","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470093733","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}