{"product_id":"9780470059852","title":"An Introduction to Statistics in Early Phase Trials","description":"\u003ch1\u003eAn Introduction to Statistics in Early Phase Trials\u003c\/h1\u003e\u003ch3\u003eSteven Julious | Say Beng Tan | David Machin\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eAll new medicines and devices undergo early phase trials to assess, interpret and better understand their efficacy, tolerability and safety. \u003ci\u003eAn Introduction to Statistics in Early Phase Trials\u003c\/i\u003e describes the practical design and analysis of these important early phase clinical trials and provides the crucial statistical basis for their interpretation. It clearly and concisely provides an overview of the most common types of trials undertaken in early phase clinical research and explains the different methodologies used. The impact of statistical technologies on clinical development and the statistical and methodological basis for making clinical and investment decisions are also explained.  \u003cul\u003e \u003cli\u003eConveys key ideas in a concise manner understandable by non-statisticians\u003c\/li\u003e \u003cli\u003eExplains how to optimise designs in a constrained or fixed resource setting\u003c\/li\u003e \u003cli\u003eDiscusses decision making criteria at the end of Phase II trials\u003c\/li\u003e \u003cli\u003eHighlights practical day-to-day issues and reporting of early phase trials\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eAn Introduction to Statistics in Early Phase Trials\u003c\/i\u003e is an essential guide for all researchers working in early phase clinical trial development, from clinical pharmacologists and pharmacokineticists through to clinical investigators and medical statisticians. It is also a valuable reference for teachers and students of pharmaceutical medicine learning about the design and analysis of clinical trials.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e \u003cb\u003eSteven A. Julious\u003c\/b\u003e, Medical Statistics Group, School of Health and Related Research, University of Sheffield, UK.  \u003cp\u003e\u003cb\u003eSay-Beng Tan\u003c\/b\u003e, Singapore Clinical Research Institute and Duke-NUS Graduate Medical School, Singapore.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDavid Machin\u003c\/b\u003e, Children's Cancer and Leukaemia Group (CCLG), University of Leicester, UK.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e05 April 2010\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470059852\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e272\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e21.92\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44378518093964,"sku":"9780470059852","price":112.46,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470059852.jpg?v=1780197311","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470059852","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}