{"product_id":"9780470028766","title":"Validation of Cell-Based Assays in the GLP Setting A Practical Guide","description":"\u003ch1\u003eValidation of Cell-Based Assays in the GLP Setting\u003c\/h1\u003e\u003ch2\u003eA Practical Guide\u003c\/h2\u003e\u003ch3\u003eUma Prabhakar | Marian Kelley\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Biotechnology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eThe use of cell-based assays within pharmaceutical and biotechnology companies is driven in large part by the need to evaluate the plethora of drug targets derived from genomics and proteomics. In addition, the potential of biomarkers to facilitate the development of effective and safe drugs is being recognized as an integral part of all phases of drug development, and cell-based technologies are a critical part of biomarker discovery and development. Despite this critical role, cell-based assays have not been standardized and made compliant with Good Laboratory Practice guidelines.    \u003cp\u003eIn this book, the editors have collected assays for which validation procedures have been developed, making this a vital purchase for anyone using such assays in drug development.\u003c\/p\u003e \u003cp\u003eThis book: \u003c\/p\u003e \u003cul\u003e \u003cli\u003eDescribes the development, optimization and validation of cell-based assays, including procedural documentation required for Good Laboratory Practice\u003c\/li\u003e \u003cli\u003ePresents validations of cell-based assays for select targets, with step-by-step instructions, allowing the reader to reproduce the assay conditions and results\u003c\/li\u003e \u003cli\u003eProvides details of techniques used in the evaluation of immunodeficiency, autoimmune and oncological disorders, including assessment of cancer vaccines\u003c\/li\u003e \u003cli\u003eOffers a compendium of validation parameters that need to be considered when using these methods to develop a new drug\u003c\/li\u003e \u003cli\u003eIncludes detailed protocols for the evaluation of cytokines and of neutralizing antibodies directed against protein therapeutics\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eValidation of Cell-based Assays in the GLP Setting\u003c\/i\u003e provides the professional with an invaluable reference source, featuring key guidelines. The book will prove extremely useful to all scientists working in the areas of drug development. \u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cb\u003eUma Prabhakar\u003c\/b\u003e, Ph. D. Director, Department of Clinical Pharmacology \u0026amp; Experimental Medicine, Centocor Inc, PA, USA  \u003cp\u003e\u003cb\u003eMarian Kelley,\u003c\/b\u003e M.A., Director of Compliance, Department of Clinical Pharmacology \u0026amp; Experimental Medicine, Centocor Inc, PA, USA\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e12 May 2008\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470028766\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e320\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e25.0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44379844542604,"sku":"9780470028766","price":188.96,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470028766_2070d5b7-eb2a-4e6c-8995-6898b3140a46.jpg?v=1780236968","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470028766","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}