{"product_id":"9780470014882","title":"Neurodegenerative Diseases and Metal Ions, Volume 1","description":"\u003ch1\u003eNeurodegenerative Diseases and Metal Ions, Volume 1\u003c\/h1\u003e \u003ch2\u003eSigel, Astrid; Sigel, Helmut; Sigel, Roland K. O.\u003c\/h2\u003e \u003cp\u003e\u003cb\u003eAbout the Series...\u003c\/b\u003e  \u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMetal Ions in Life Sciences\u003c\/i\u003e\u003c\/b\u003e links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between the chemistry of metals and life processes. The series reflects the interdisciplinary nature of \u003ci\u003eBiological Inorganic Chemistry\u003c\/i\u003e and coordinates the efforts of scientists in fields like biochemistry, inorganic chemistry, coordination chemistry, molecular and structural biology, enzymology, environmental chemistry, physiology, toxicology, biophysics, pharmacy, and medicine. Consequently, the volumes are an essential source for researchers active in these and related fields as well as teachers preparing courses, e.g., in \u003ci\u003eBioinorganic Chemistry\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAbout this Book...\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 1,\u003c\/b\u003e devoted solely to the vital research area concerning the role of metal ions in neurodegenerative diseases, offers in 15 stimulating chapters an authoritative and timely view of this fascinating subject.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eWritten by \u003cb\u003e41\u003c\/b\u003e internationally recognized experts\u003c\/i\u003e, \u003cb\u003e\u003ci\u003eNeurodegenerative Diseases and Metal Ions\u003c\/i\u003e\u003c\/b\u003e highlights, supported by \u003cb\u003e130\u003c\/b\u003e illustrations, the recent progress made in understanding the role metal ions play in diseases like transmissible spongiform encephalopathies (Creutzfeldt-Jakob and related diseases), Alzheimer's, Parkinson's, Huntington's, Wilson's and Menkes' diseases, as well as in familial amyotrophic lateral sclerosis and others. The interplay between metal ions, catecholamines and the formation of reactive oxygen species resulting in oxidative stress is considered, as is the metalloneurochemistry of zinc and the neurotoxicity of aluminum, cadmium, lead, and mercury. The need for novel drugs which manipulate metal-centered neuropathology is emphasized.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Wiley\u003c\/p\u003e \u003cp\u003ePublication Date: 2006-05-12\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003e ISBN-10: 9780470014882\u003c\/p\u003e \u003cp\u003eISBN-13: 9780470014882\u003c\/p\u003e \u003cp\u003eDOI: \u003c\/p\u003e \u003cp\u003eDimensions: 237.00cm x159.00cm\u003c\/p\u003e \u003cp\u003ePages: 488\u003c\/p\u003e ","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44380541419660,"sku":"9780470014882","price":269.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470014882.jpg?v=1755191647","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470014882","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}