Genetically Engineered Mice for Cancer Research: design, analysis, pathways, validation and pre-clinical testing

Green, Jeffrey E.; Ried, Thomas

Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology. Additionally, these models are emerging as important pre-clinical systems in which to test cancer prevention and therapeutic strategies in order to select compounds for testing in clinical trials.

Details

Published by: Springer

Publication Date: 2011-12-08

Format: Hardcover

ISBN-13: 9780387698038

DOI: 10.1007/978-0-387-69805-2

Dimensions: 235cm x155cm

Pages: 632