{"product_id":"9780387690735","title":"The Kinetochore:: From Molecular Discoveries to Cancer Therapy","description":"\u003ch1\u003eThe Kinetochore:: From Molecular Discoveries to Cancer Therapy\u003c\/h1\u003e \u003ch2\u003eDe Wulf, Peter; Earnshaw, William\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eKinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s. “\u003cem\u003eThe Kinetochore: from Molecular Discoveries to Cancer Therapy” \u003c\/em\u003epresents a thorough up-to-date analysis of kinetochore and centromere composition, formation, regulation, and activity, both in mitosis and meiosis, in humans and “model” eukaryotic species, and at natural and mutant neocentromeres. Recently initiated translational research on kinetochores is also discussed as kinetochores are being mined as a very rich target for the next generations of anti-cancer drugs.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2008-11-11\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9780387690735\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-0-387-69076-6\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 516\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":49472031064204,"sku":"9780387690735","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780387690735.jpg?v=1777987812","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780387690735","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}