{"product_id":"9780387277813","title":"Statistical Monitoring of Clinical Trials: Fundamentals for Investigators","description":"\u003ch1\u003eStatistical Monitoring of Clinical Trials: Fundamentals for Investigators\u003c\/h1\u003e \u003ch2\u003eMoyé, Lemuel A.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eStatistical Monitoring of Clinical Trials: Fundamentals for Investigators introduces the investigator and statistician to monitoring procedures in clinical research. Clearly presenting the necessary background with limited use of mathematics, this book increases the knowledge, experience, and intuition of investigations in the use of these important procedures now required by the many clinical research efforts. \u003c\/p\u003e\n\u003cp\u003eThe author provides motivated clinical investigators the background, correct use, and interpretation of these monitoring procedures at an elementary statistical level. He defines terms commonly used such as group sequential procedures and stochastic curtailment in non-mathematical language and discusses the commonly used procedures of Pocock, O’Brien–Fleming, and Lan–DeMets. He discusses the notions of conditional power, monitoring for safety and futility, and monitoring multiple endpoints in the study. The use of monitoring clinical trials is introduced in the context of the evolution of clinical research and one chapter is devoted to the more recent Bayesian procedures. \u003c\/p\u003e\n\u003cp\u003eFrom the reviews:\u003c\/p\u003e\n\u003cp\u003e\"The author has a wealth of experience in this area and this is demonstrated throughout the text with relevant poignant examples.\" \u003cem\u003eShort Book Reviews of the ISI, June 2006\u003c\/em\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2005-11-16\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9780387277813\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/0-387-27782-X\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 254\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":46541662421132,"sku":"9780387277813","price":49.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780387277813.jpg?v=1775744963","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780387277813","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}