Protein Reviews: Part A: Protein Aggregation and Conformational Diseases

Uversky, Vladimir N.; Fink, Anthony

This volume fills the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. It is devoted to the general questions of conformational disorders and includes discussion of involvement of such common factors as molecular chaperones, oxidative damage, proteasome, glycosoaminoglycans, serum amyloid protein P and several others in the development of different disorders. Some experimental techniques applicable for the visualization of protein deposition in vivo and in vitro are also present.

Details

Published by: Springer

Publication Date: 2006-06-13

Format: Hardcover

ISBN-13: 9780387259185

DOI: 10.1007/b136464

Dimensions: 235cm x155cm

Pages: 419